Abstract
Prenatal diagnosis of congenital anomalies provides an opportunity to prepare and counsel parents. It can lead to pregnancy termination; to a change in timing, mode, or location of delivery; or, in some cases, to prenatal intervention. Families with an affected fetus are best managed by a cohesive medical team. This article outlines the principles used to manage these cases.
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- Adzick N. S., Harrison M. R., Glick P. L., Anderson J., Villa R. L., Flake A. W., Laberge J. M. Fetal surgery in the primate. III. Maternal outcome after fetal surgery. J Pediatr Surg. 1986 Jun;21(6):477–480. doi: 10.1016/s0022-3468(86)80215-9. [DOI] [PubMed] [Google Scholar]
- Adzick N. S., Harrison M. R., Glick P. L., Golbus M. S., Anderson R. L., Mahony B. S., Callen P. W., Hirsch J. H., Luthy D. A., Filly R. A. Fetal cystic adenomatoid malformation: prenatal diagnosis and natural history. J Pediatr Surg. 1985 Oct;20(5):483–488. doi: 10.1016/s0022-3468(85)80470-x. [DOI] [PubMed] [Google Scholar]
- Arnold A. J., Rickwood A. M. Natural history of pelviureteric obstruction detected by prenatal sonography. Br J Urol. 1990 Jan;65(1):91–96. doi: 10.1111/j.1464-410x.1990.tb14666.x. [DOI] [PubMed] [Google Scholar]
- Berseth C. L., Malachowski N., Cohn R. B., Sunshine P. Longitudinal growth and late morbidity of survivors of gastroschisis and omphalocele. J Pediatr Gastroenterol Nutr. 1982;1(3):375–379. doi: 10.1097/00005176-198201030-00017. [DOI] [PubMed] [Google Scholar]
- Bond S. J., Harrison M. R., Schmidt K. G., Silverman N. H., Flake A. W., Slotnick R. N., Anderson R. L., Warsof S. L., Dyson D. C. Death due to high-output cardiac failure in fetal sacrococcygeal teratoma. J Pediatr Surg. 1990 Dec;25(12):1287–1291. doi: 10.1016/0022-3468(90)90535-h. [DOI] [PubMed] [Google Scholar]
- Crombleholme T. M., Harrison M. R., Golbus M. S., Longaker M. T., Langer J. C., Callen P. W., Anderson R. L., Goldstein R. B., Filly R. A. Fetal intervention in obstructive uropathy: prognostic indicators and efficacy of intervention. Am J Obstet Gynecol. 1990 May;162(5):1239–1244. doi: 10.1016/0002-9378(90)90026-4. [DOI] [PubMed] [Google Scholar]
- Glick P. L., Harrison M. R., Adzick N. S., Noall R. A., Villa R. L. Correction of congenital hydronephrosis in utero IV: in utero decompression prevents renal dysplasia. J Pediatr Surg. 1984 Dec;19(6):649–657. doi: 10.1016/s0022-3468(84)80348-6. [DOI] [PubMed] [Google Scholar]
- Hancock B. J., Wiseman N. E. Congenital duodenal obstruction: the impact of an antenatal diagnosis. J Pediatr Surg. 1989 Oct;24(10):1027–1031. doi: 10.1016/s0022-3468(89)80208-8. [DOI] [PubMed] [Google Scholar]
- Harrison M. R., Adzick N. S., Jennings R. W., Duncan B. W., Rosen M. A., Filly R. A., Goldberg J. D., deLorimier A. A., Golbus M. S. Antenatal intervention for congenital cystic adenomatoid malformation. Lancet. 1990 Oct 20;336(8721):965–967. doi: 10.1016/0140-6736(90)92420-m. [DOI] [PubMed] [Google Scholar]
- Harrison M. R., Adzick N. S., Longaker M. T., Goldberg J. D., Rosen M. A., Filly R. A., Evans M. I., Golbus M. S. Successful repair in utero of a fetal diaphragmatic hernia after removal of herniated viscera from the left thorax. N Engl J Med. 1990 May 31;322(22):1582–1584. doi: 10.1056/NEJM199005313222207. [DOI] [PubMed] [Google Scholar]
- Harrison M. R., Langer J. C., Adzick N. S., Golbus M. S., Filly R. A., Anderson R. L., Rosen M. A., Callen P. W., Goldstein R. B., deLorimier A. A. Correction of congenital diaphragmatic hernia in utero, V. Initial clinical experience. J Pediatr Surg. 1990 Jan;25(1):47–57. doi: 10.1016/s0022-3468(05)80163-0. [DOI] [PubMed] [Google Scholar]
- Harrison M. R., Nakayama D. K., Noall R., de Lorimier A. A. Correction of congenital hydronephrosis in utero II. Decompression reverses the effects of obstruction on the fetal lung and urinary tract. J Pediatr Surg. 1982 Dec;17(6):965–974. doi: 10.1016/s0022-3468(82)80476-4. [DOI] [PubMed] [Google Scholar]
- Hasan S., Hermansen M. C. The prenatal diagnosis of ventral abdominal wall defects. Am J Obstet Gynecol. 1986 Oct;155(4):842–845. doi: 10.1016/s0002-9378(86)80035-7. [DOI] [PubMed] [Google Scholar]
- Hughes M. D., Nyberg D. A., Mack L. A., Pretorius D. H. Fetal omphalocele: prenatal US detection of concurrent anomalies and other predictors of outcome. Radiology. 1989 Nov;173(2):371–376. doi: 10.1148/radiology.173.2.2678251. [DOI] [PubMed] [Google Scholar]
- Kurjak A., Zalud I., Jurković D., Alfirević Z., Tomić K. Ultrasound diagnosis and evaluation of fetal tumors. J Perinat Med. 1989;17(3):173–193. doi: 10.1515/jpme.1989.17.3.173. [DOI] [PubMed] [Google Scholar]
- Langer J. C., Adzick N. S., Filly R. A., Golbus M. S., deLorimier A. A., Harrison M. R. Gastrointestinal tract obstruction in the fetus. Arch Surg. 1989 Oct;124(10):1183–1187. doi: 10.1001/archsurg.1989.01410100085014. [DOI] [PubMed] [Google Scholar]
- Langer J. C., Bell J. G., Castillo R. O., Crombleholme T. M., Longaker M. T., Duncan B. W., Bradley S. M., Finkbeiner W. E., Verrier E. D., Harrison M. R. Etiology of intestinal damage in gastroschisis, II. Timing and reversibility of histological changes, mucosal function, and contractility. J Pediatr Surg. 1990 Nov;25(11):1122–1126. doi: 10.1016/0022-3468(90)90745-u. [DOI] [PubMed] [Google Scholar]
- Langer J. C., Fitzgerald P. G., Desa D., Filly R. A., Golbus M. S., Adzick N. S., Harrison M. R. Cervical cystic hygroma in the fetus: clinical spectrum and outcome. J Pediatr Surg. 1990 Jan;25(1):58–62. doi: 10.1016/s0022-3468(05)80164-2. [DOI] [PubMed] [Google Scholar]
- Langer J. C., Harrison M. R., Adzick N. S. Congenital diaphragmatic hernia: current controversies in prenatal and postnatal management. Fetal Ther. 1987;2(4):209–215. doi: 10.1159/000263319. [DOI] [PubMed] [Google Scholar]
- Langer J. C., Harrison M. R., Schmidt K. G., Silverman N. H., Anderson R. L., Goldberg J. D., Filly R. A., Crombleholme T. M., Longaker M. T., Golbus M. S. Fetal hydrops and death from sacrococcygeal teratoma: rationale for fetal surgery. Am J Obstet Gynecol. 1989 May;160(5 Pt 1):1145–1150. doi: 10.1016/0002-9378(89)90177-4. [DOI] [PubMed] [Google Scholar]
- Manning F. A., Harrison M. R., Rodeck C. Catheter shunts for fetal hydronephrosis and hydrocephalus. Report of the International Fetal Surgery Registry. N Engl J Med. 1986 Jul 31;315(5):336–340. doi: 10.1056/NEJM198607313150532. [DOI] [PubMed] [Google Scholar]
- Nakayama D. K., Harrison M. R., Seron-Ferre M., Villa R. L. Fetal surgery in the primate II. Uterine electromyographic response to operative procedures and pharmacologic agents. J Pediatr Surg. 1984 Aug;19(4):333–339. doi: 10.1016/s0022-3468(84)80248-1. [DOI] [PubMed] [Google Scholar]
- Sermer M., Benzie R. J., Pitson L., Carr M., Skidmore M. Prenatal diagnosis and management of congenital defects of the anterior abdominal wall. Am J Obstet Gynecol. 1987 Feb;156(2):308–312. doi: 10.1016/0002-9378(87)90274-2. [DOI] [PubMed] [Google Scholar]
- Sipes S. L., Weiner C. P., Sipes D. R., 2nd, Grant S. S., Williamson R. A. Gastroschisis and omphalocele: does either antenatal diagnosis or route of delivery make a difference in perinatal outcome? Obstet Gynecol. 1990 Aug;76(2):195–199. [PubMed] [Google Scholar]
- Suruga K., Miyano T., Kimura K., Arai T., Kojima Y. Reoperation in the treatment of biliary atresia. J Pediatr Surg. 1982 Feb;17(1):1–6. doi: 10.1016/s0022-3468(82)80315-1. [DOI] [PubMed] [Google Scholar]