Figure 8. Effect of captopril treatment on cardiovascular parameters of H-Ras^G12V mutant mice.

Systolic arterial pressure (A), LV and RV cardiomyocyte area (B), and total heart weight (C) in H-Ras^+/+ (white bars) and H-Ras^G12V (black bars) mice that were left untreated or treated with captopril for 12 or 24 weeks. Untreated mice were controls for the 24-week treatment protocol. *P < 0.01 versus H-Ras^+/+.