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MKK7 is an activator of the JNK signal transduction pathway. The ERK, BMK1/ERK5, p38, and JNK signal transduction pathways are illustrated schematically. MKK1 and MKK2 are activators of the ERK subgroup of MAP kinase. MKK3, MKK4, and MKK6 are activators of p38 MAP kinase. MKK5 is an activator of BMK1/ERK5. MKK7 is a specific activator of the JNK group of MAP kinases, whereas MKK4 activates both the p38 and JNK subgroups of MAP kinase.
