Figure 4.
Macro- and microscopic changes of epidermis from wild-type and skin-specific, Pig-a-disrupted mouse (Cre:Pig-aflox male mouse). (A) Macroscopic appearance of the wild-type and the skin-specific, Pig-a-disrupted mouse. (B) Histological examination of the epidermis from the wild-type and the skin-specific, disrupted mouse. (Hematoxylin-eosin staining, ×200.) (C) Histological examination of the horny layers by electron microscopy. The vesicles in the horny layers are indicated by white arrows.