TABLE 1.
Effects of baclofen on the bursting properties of ET cells
CNQX + APV + Gabazine | Baclofen | CGP55845 | |
---|---|---|---|
Spike frequency, Hz | 9.7 ± 1.7 | 6.9 ± 1.6** | 9.2 ± 1.5** |
Intraburst frequency,Hz | 88.0 ± 9.5 | 103.0 ± 10.0** | 81.5 ± 10.0** |
Burst frequency, Hz | 2.5 ± 0.5 | 1.8 ± 0.5*** | 2.2 ± 0.5** |
Burst duration, ms | 42.0 ± 6.0 | 47.0 ± 6.0* | 44.0 ± 6.0 |
Number of spikes/burst | 4.6 ± 0.4 | 5.7 ± 0.5** | 4.6 ± 0.4** |
Burst interspike interval slope, ms/interval | 5.6 ± 1.2 | 3.4 ± 0.84** | 5.9 ± 1.4** |
Values are means ± SE; n = 10. Values in each column were statistically compared to the corresponding values in the previous column:
P < 0.05,
P < 0.01,
P < 0.001.