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. Author manuscript; available in PMC: 2008 May 13.
Published in final edited form as: Neuroscience. 2006 Jul 28;142(1):203–221. doi: 10.1016/j.neuroscience.2006.05.068

Fig. 7.

Fig. 7

Modeling of spatial distribution of a glomerular field potential. Two imaginary partial modules that together constitute the whole structural functional ensemble contribute differently in the entire field. (A) Glomerular sphere with negatively charged dendritic neuropil (red) and the outer shell of JG cell bodies (blue); a segment of the glomerulus is removed to show its core. (B) Tufted and mitral cells concentrate tufts of their primary dendrites in a single glomerulus (red ball); soma and secondary dendrites of tufted cells (green slab) as well as soma and lateral dendrites of mitral cells (blue slab) are uniformly distributed in the EPL. (C) Field potential profiles generated by different components of the entire module. PG-s and ET-s stand for contribution of PG and ET somata located in the glomerular shell; T-s/d and M-s/d designate impact of tufted and mitral somato-dendritic compartments located in the EPL and MCL; M-tuft, T-tuft, ET-tuft and PG-d are fields generated by intraglomerular dendritic arborizations of the corresponding cell types. Total field is the sum of all the above partial fields. Vertical dashed line indicates the core/shell border. (D) Separate contributions of all neuron types to the total field of the module; JG profile is the sum of PG and ET profiles. Two central dashed lines designate neuropil/shell borders with a ~10 μm wall of cell bodies between two adjacent glomeruli; dashed line on the right indicates the center of adjacent glomerulus. (E) xy Projection of the flattened glomerulus (colored oval); dashed circle behind the oval designates an original glomerular sphere. (F) Spatial profile of the glomerular field is practically independent of glomerular deformation. Vertical dashed lines designate neuropil/shell border in the non-distorted sphere (middle), along the short axis (left) and along the long axis (right); horizontal dashed line designates 30% of sGLFPmax and shows persistency of the field magnitude at the neuropil/shell border regardless of the glomerulus deformation. Distance on all plots is measured from the center of the glomerulus in the plane parallel to the MOB layers. Partial field magnitudes are normalized to the maximum of the total field.