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Functional and physiological parameters of 12- and 20-week-old isolated working mdx and mdx/GC+/0 mouse hearts. Data are means ± SEM of mdx (solid bars) and mdx/GC+/0 (open bars) heart perfusion experiments (n = 4 mice per group). Values shown represent averages for the 20- to 30-min perfusion period. *, P < 0.05; **, P < 0.001 mdx vs. mdx/GC+/0 mouse hearts. LVEDP, left ventricular end-diastolic pressure; RPP, rate-pressure product.
