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. 2008 May 12;105(19):7028–7033. doi: 10.1073/pnas.0710595105

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© 2008 by The National Academy of Sciences of the USA

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Fig. 3. — Heart rate responses and quantitation of in vivo cardiomyocyte sarcolemmal injury induced by an acute increase in cardiac mechanical stress after isoproterenol infusion in mdx and mdx/GC^+/0 mice. Values are means ± SEM of four to six experiments in mdx (solid bars) or mdx/GC^+/0 (open bars) mouse hearts. Heart rate was continuously monitored by a single-lead electrocardiogram (A), and cardiomyocyte sarcolemmal injury was evaluated by using the Evans blue vital dye (B). ***, P < 0.001 for mdx vs. mdx/GC^+/0 mouse hearts.