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Numerous miRNAs are down-regulated in late-stage or high-grade ovarian cancer. (A) Heat map showing the 44 miRNAs significantly down-regulated in late-stage relative to early-stage EOC. (B) Heat map showing the 13 miRNAs significantly down-regulated in high-grade relative to low-grade EOC. (C) Heat map showing the miRNAs significantly down-regulated in late-stage or high-grade serous EOC. (D) Venn diagrams of down-regulated miRNAs in different analyses.
