Table 3.
Daptomycin eluted from calcium sulfate pellets†
| μg/ml/ginit | ||||
|---|---|---|---|---|
| Days | Nonsterilized, laboratory | Std Dev | Sterilized, laboratory | Std Dev |
| 1 | 537.2 | (148.4) | 303.5 | (37.2) |
| 2 | 153.5 | (39.1) | 153.6 | (13.8) |
| 3 | 37.2 | (15.6) | 43.9 | (23.2) |
| 7 | 5.5 | (1.7) | 4.6 | (1.3) |
| 10 | 6.9 | (1.5) | 4.1 | (1.1) |
| 14 | 5.8 | (3.9) | 3.9 | (1.6) |
| 21 | 4.8 | (1.5) | 4.8 | (0.8) |
| 28 | 7.2 | (4.7) | 4.5 | (1.7) |
| Days | Clinical | Std Dev | ||
| 1 | 697.4 | (7.1) | ||
| 2 | 116.8 | (27.0) | ||
| 3 | 21.9 | (1.8) | ||
| 4 | 6.4 | (0.3) | ||
| 5 | 7.5 | (0.4) | ||
| 7 | 7.1 | (1.5) | ||
| 11 | 7.7 | (2.2) | ||
| 15 | 6.0 | (1.8) | ||
| 21 | 7.7 | (1.2) | ||
| 28 | 5.6 | (2.4) | ||
†Note: All concentrations have been divided by initial pellet weight, in grams.