. 2008 Apr 25;466(6):1292–1301. doi: 10.1007/s11999-008-0252-1

Table 2.

Treatment results of nonmetastatic extremity OGS: historical controls

Reference	Type of study	Age	# Pts	Overall survival	EFS	Site	>90% Response	Rate of local recurrence
Lewis et al. [35]	Randomized 2 arm	<40	497	55% (C)	NA	Extremity	36% (C)	18% (C)
				58% (D)			50% (D)	9% (D)
				5 yr			50% (D)	9% (D)
Ferrari et al. [22]	Single arm	<40	182	77%	64%	Extremity	42%	4%
Ferrari et al. [22]	Single arm	<40	182	8 yr	8 yr	Extremity	42%	4%
Bacci et al. [6]	Retrospective	All	789	68%	60%	All	63%	5%
Bacci et al. [6]	Retrospective	All	789	5 yr	5 yr	All	63%	5%
Ferrari et al. [20]	Randomized 2 arm	<40	303	72% (1)	63% (1)	Extremity	NA (1)	Not included
				61% (2)	54% (2)		64% (2)
				8 yr	8 yr		64% (2)
Bacci et al. [5]	Retrospective	All	1126	66%	55%	Extremity	NA	5%
Bacci et al. [5]	Retrospective	All	1126	5 yr	5 yr	Extremity	NA	5%
Bacci et al. [3]	Single arm	All	43	68%	53%	Extremity	56%	5%
Bacci et al. [3]	Single arm	All	43	7 yr	7 yr	Extremity	56%	5%
Present Study	Retrospective	18–77	53	82%	79%	Extremity	77%	4%
Present Study	Retrospective	18–77	53	10 yr	10 yr	Extremity	77%	4%