Table 2.
Skin reactions in guinea pigs sensitized with the live MTB (mean ± s.d. mm in diameter) | ||||
---|---|---|---|---|
Groups | Doses | No. of animals | 24 h | 48 h |
PBS | 6 | 0 | 0 | |
PPD | 5 IU | 6 | 10·00 ± 2·09 | 7·92 ± 1·77 |
rESAT6 | 0·4 μg | 6 | 9·42 ± 1·63 | 7·17 ± 2·14 |
0·6 μg | 6 | 10·17 ± 2·32 | 7·97 ± 2·67 | |
0·8 μg | 6 | 10·92 ± 3·12 | 8·50 ± 2·81 | |
1·0 μg | 6 | 10·50 ± 2·17 | 7·67 ± 2·18 |
PBS, phosphate-buffered saline; PPD, purified protein derivative; s.d., standard deviation.