Table 1.
Human serum immunoglobulin G (IgG) subclass reactivity with crude malaria antigen and C231 in different age groups. Values represent enzyme-linked immunosorbent assay units, mean ± standard error.
| Crude malaria antigen (F32) | C231 | |||||||
|---|---|---|---|---|---|---|---|---|
| Age (years) | IgG1 | IgG2 | IgG3 | IgG4 | IgG1 | IgG2 | IgG3 | IgG4 |
| 4–9 (n = 15) | 119 ± 46·6 | 1·1 ± 0·71 | 4·1 ± 1·2 | 0·5 ± 0·92 | 0·37 ± 0·13 | 0·1 ± 0·04 | 1·0 ± 0·91 | 0·08 ± 0·023 |
| P-value | 0·76 | 0·84 | 0·02 | 0·46 | 0·14 | 0·0013 | 0·0097 | 0·64 |
| 10–14 (n = 17) | 109 ± 35·3 | 0·93 ± 0·27 | 9·3 ± 2·3 | 0·56 ± 0·17 | 0·83 ± 0·44 | 1·8 ± 0·69 | 1·7 ± 0·71 | 0·66 ± 0·34 |
| P-value | 0·0091 | 0·067 | 0·013 | 0·87 | 0·016 | 0·075 | 0·0048 | 0·23 |
| 15–19 (n = 18) | 486 ± 194 | 8·8 ± 4·0 | 15·3 ± 1·9 | 0·68 ± 0·18 | 1·1 ± 0·36 | 4·0 ± 2·2 | 4·7 ± 1·2 | 0·72 ± 0·26 |
| P-value | 0·53 | 0·39 | 0·57 | 0·60 | 0·23 | 0·43 | 0·91 | 0·81 |
| 20–87 (n = 50) | 504 ± 108 | 9·9 ± 2·4 | 18·6 ± 1·9 | 0·55 ± 0·1 | 22·1 ± 8·4 | 6·3 ± 1·2 | 6·2 ± 0·98 | 1·2 ± 0·34 |