Table 1.
Survival of ZPI and PZ gene-deleted mice
| Mating pairs | ZPI, N (%) | PZ, N (%) | ZPI vs PZ |
|---|---|---|---|
| Het × Het | |||
| 6 weeks | |||
| WT | 116 (30) | 157 (27) | |
| Het | 194 (50) | 309 (52) | |
| KO | 75 (20) | 126 (21) | |
| P | .013 | .111 | .448 |
| FV/(λ/λ)/Het × FV(λ/λ)/Het | |||
| 6 weeks | |||
| FV(λ/λ)/WT | 23 (77) | 24 (67) | |
| FV(λ/λ)/Het | 7 (23) | 12 (33) | |
| FV(λ/λ)/KO | 0 (0) | 0 (0) | |
| P | < .001 | < .001 | .372 |
| E18.5 | |||
| FV(λ/λ)/WT | 13 (57) | 7 (21) | |
| FV(λ/λ)/Het | 9 (39) | 18 (53) | |
| FV(λ/λ)/KO | 1 (4) | 9 (26) | |
| P | .001 | .838 | .009 |
| E13.5 | |||
| FV(λ/λ)/WT | 4 (24) | ||
| FV(λ/λ)/Het | 8 (47) | ND | |
| FV(λ/λ)/KO | 5 (29) | ||
| P | .916 | ||
| FV/(λ/λ)/Het × FV(+/+)/Het | |||
| 6 weeks | |||
| FV(λ/+)/WT | 39 (40) | 40 (26) | |
| FV(λ/+)/Het | 41 (42) | 86 (55) | |
| FV(λ/+)/KO | 17 (18) | 30 (19) | |
| P | .002 | .232 | .047 |
Numbers in italics are derived from Yin et al.12
E indicates embryonic day; and ND, not determined.