Abstract
Squalene analogs such as lycopersene, geranylfarnesyl, digeranyl, and 2-hydroxy-2,3-dihydrosqualene and terpene alcohol derivatives such as farnesyl benzyl ether, farnesyl pivalate, geranylgeranyl pivalate, geranyl pivalate, and geranyl benzyl ether were oxidized by Corynebacterium sp. strain SY-79, which was isolated from soil by using squalene as a carbon source. Lycopersene and geranylfarnesyl gave no major product. Digeranyl, geranyl benzyl ether, and geranyl pivalate gave terminal oxidation products, and 2-hydroxy-2,3-dihydrosqualene, farnesyl benzyl ether, farnesyl pivalate, and geranylgeranyl pivalate were degraded to give lower molecular carboxylic acids. Strain SY-79 showed promising oxidative activities toward acyclic terpenes, although the metabolites obtained were variable, depending upon the structure of the substrate.
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Selected References
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- Seo C. W., Yamada Y., Takada N., Okada H. Microbial Transformation of Squalene: Terminal Methyl Group Oxidation by Corynebacterium sp. Appl Environ Microbiol. 1983 Feb;45(2):522–525. doi: 10.1128/aem.45.2.522-525.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Yamada Y., Kusuhara N., Okada H. Oxidation of linear terpenes and squalene variants by Arthrobacter sp. Appl Environ Microbiol. 1977 Apr;33(4):771–776. doi: 10.1128/aem.33.4.771-776.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Yamada Y., Motoi H., Kinoshita S., Takada N., Okada H. Oxidative degradation of squalene by Arthrobacter species. Appl Microbiol. 1975 Mar;29(3):400–404. doi: 10.1128/am.29.3.400-404.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]