| Occludin |
|
| Tight junction fraction (all mobile) |
80% |
| Lateral membrane fraction (all mobile) |
20% |
| Intracellular fraction |
0% |
| Tight junction diffusion constant |
0.011 μm2s−1
|
| Lateral membrane diffusion constant |
0.1 μm2s−1
|
| Rate constant for movement to tight junction (Kf) |
0.0040 s−1
|
| Rate constant for movement from tight junction (Kr) |
0.0010 s−1
|
| Claudin-1 |
|
| Tight junction fraction |
100% |
| Immobile fraction at the tight junction |
60% |
| Mobile fraction at the tight junction |
40% |
| Lateral membrane fraction |
0% |
| Intracellular fraction |
0% |
| Tight junction diffusion constant, immobile fraction |
0 μm2s−1
|
| Tight junction diffusion constant, mobile fraction |
0.011 μm2s−1
|
| ZO-1 |
|
| Tight junction fraction |
40% |
| Exchangeable fraction at the tight junction |
25% |
| Nonexchangeable fraction at the tight junction |
15% |
| Lateral membrane fraction |
0% |
| Intracellular fraction |
60% |
| Tight junction diffusion constant, exchangeable and nonexchangeable fractions |
0 μm2s−1
|
| Intracellular diffusion constant |
1 μm2s−1
|
| Rate constant for movement to tight junction (Kf), exchangeable fraction |
0.25 μm2s−1
|
| Rate constant for movement from tight junction (Kr), exchangeable fraction |
0.0075 s−1
|
| Rate constant for movement to tight junction (Kf), nonexchangeable fraction |
0 μm2s−1
|
| Rate constant for movement from tight junction (Kr), nonexchangeable fraction |
0 s−1
|
