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. 2008 May 28;3(5):e2295. doi: 10.1371/journal.pone.0002295

Figure 2. Histogram of predicted location of COG and CPG genes.

Figure 2

Protein products were tested for transmembrane (TM) domains, secretory signal sequences and glycosylphosphatidylinositol (GPI) anchor sequences. Secreted; secretory signal sequence positive TM and GPI-anchor negative, surface; TM or GPI-anchor positive, Intracellular; secretory signal, TM and GPI-anchor negative. COGs, all 1:1:1 T. brucei:T. cruzi:L. major clusters if orthologous genes. All CPG, all T. brucei CPGs. CPGs>2 members, all CPGs tested for positive selection using codon model. d N/d S>1, CPGs subject to adaptive evolution using codon models.