Table 2. Functional annotation of CPGs subject to positive selection.
Description | CPGs | Predicted Location | Size a | Pfam Domains | Biological Process | Molecular Function |
65 kDa ISG | 19416372, 21719250 | Su | 434–436 | n/d | n/d | n/d |
75 kDa ISG | 20195704 | Su | 522–523 | n/d | n/d | n/d |
Adenosine transporter | 20117965 | Su | 462–466 | MFS_1, Nucleoside_tran | transport | nucleoside transporter activity |
Amino acid transporter | 19796418, 22063411 | Su | 450–490 | Aa_trans, Trp_Tyr_perm | amino acid transport | amine transmembrane transporter activity |
EP1 procyclin | 19416463 | Su | 123–141 | n/d | n/d | n/d |
GRESAG2 | 20975481 | Su | 454–457 | n/d | n/d | n/d |
Receptor-type AC | 19651441, 20115358, 21139502, 21943524 | Su, Se | 1170–1288 | Guanylate_cyc | intracellular signalling cascade, cyclic nucleotide biosynthetic process | phosphorus-oxygen lyase activity |
RHS | 19651414, 20343633, 20439293, 20461581, 20529562, 21995461 | Se, Su, In | 557–860 | n/d | n/d | n/d |
Predicted cellular location based on GPI signal peptide and transmembrane domain prediction for each member of each cluster (see methods) Su; surface, Se; secreted, In; Intracellular. Pfam domains were detected using HMMER [47] to search the Pfam database [54]. Gene Ontology terms were linked to predicted Pfam domains using Pfam2GO (http://www.geneontology.org/). For details of gene annotation and prediction of location see methods.