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. 2008 May 28;3(5):e2283. doi: 10.1371/journal.pone.0002283

Figure 2. Spontaneous locomotion and response to methamphetamine and dizocilpine in irradiated adult rats.

Figure 2

(A) Nocturnal spontaneous locomotion (21:00–3:00) in the irradiated rats (n = 17) was significantly lower than that of control (sham-irradiated) rats (n = 17). (B) Horizontal locomotor activity during the 120-min period after administration of the psychostimulant drug methamphetamine (2 mg/kg, i.p.) in irradiated rats (n = 17) was significantly higher than that of control rats (n = 17). (C) Horizontal locomotor activity during the 120-min period after administration of dizocilpine (0.03 mg/kg, i.p.) in the irradiated rats (n = 18) was not different from that of control rats (n = 18). Data are given as means±SEM.