Table 1.
Clinical characteristics of the DCCT/EDIC cohort by gender
| Parameter | Male
|
Female
|
P | ||
|---|---|---|---|---|---|
| n | Mean ± sd | n | Mean ± sd | ||
| Age (yr) | 562 | 40 ± 7 | 452 | 39 ± 7 | 0.0632 |
| Weight (kg) | 561 | 86.8 ± 14.8 | 451 | 72.5 ± 14.9 | 0.0001 |
| BMI (kg/m2) | 551 | 27.1 ± 3.9 | 439 | 26.3 ± 4.3 | 0.0055 |
| Waist-hip ratio | 550 | 0.9 ± 0.1 | 438 | 0.8 ± 0.1 | 0.0001 |
| Duration of diabetes (yr) | 562 | 17.2 ± 4.7 | 452 | 17.7 ± 4.9 | 0.0743 |
| HbA1c (%) | 555 | 8.2 ± 1.3 | 447 | 8.2 ± 1.4 | 0.8643 |
| DCCT group | 562 | 1.5 ± 0.5 | 452 | 1.5 ± 0.5 | 0.287 |
| SBP (mm Hg) | 551 | 122.0 ± 13.3 | 439 | 116.0 ± 13.8 | 0.0001 |
| DBP (mm Hg) | 551 | 77.1 ± 9.3 | 439 | 72.6 ± 9.0 | 0.0001 |
| MBP (mm Hg) | 551 | 92.3 ± 9.6 | 439 | 87.1 ± 9.6 | 0.0001 |
| LDL (mg/dl) | 529 | 118.5 ± 31.2 | 423 | 110.0 ± 29.8 | 0.0001 |
| Total cholesterol (mg/dl) | 533 | 189.7 ± 36.2 | 424 | 188.2 ± 33.8 | 0.5162 |
| Triglycerides (mg/dl) | 533 | 98.0 ± 70.9 | 424 | 77.2 ± 49.3 | 0.0001 |
| HDL (mg/dl) | 533 | 51.6 ± 12.9 | 424 | 62.7 ± 14.8 | 0.0001 |
| Log AER (mg/24 h) | 553 | 2.8 ± 1.5 | 446 | 2.5 ± 1.3 | 0.0011 |
| Common IMT (mm) | 520 | 0.60 ± 0.09 | 415 | 0.56 ± 0.08 | 0.0001 |
| Internal IMT (mm) | 511 | 0.67 ± 0.24 | 401 | 0.62 ± 0.18 | 0.0002 |
| % Hypertensive | 554 | 44 ± 49 | 442 | 26 ± 44 | 0.0001 |
Variables were evaluated between groups using t and χ2 test for continuous and categorical variables, respectively. HDL, High-density lipoprotein.