Table 2.
Associations of CAG biallelic mean with PCOS
| PCOS (%) | Controls (%) | OR (95% CI) | P valuea | |
|---|---|---|---|---|
| Combined cohort (n = 556) | ||||
| Biallelic mean less than median | 50.2 | 41.4 | 2.08 (1.32–3.30) | 0.0018 |
| X-weighted biallelic mean less than median | 54.3 | 48.4 | 1.74 (1.10–2.74) | 0.017 |
| Whites (n = 435) | ||||
| Biallelic mean less than 22 | 48.9 | 40.0 | 1.73 (1.02–2.92) | 0.041 |
| X-weighted biallelic mean less than 22 | 55.1 | 48.2 | 1.76 (1.04–2.96) | 0.034 |
| Blacks (n = 121) | ||||
| Biallelic mean less than 20 | 59.5 | 44.0 | 3.73 (1.35–10.32) | 0.011 |
| X-weighted biallelic mean less than 20 | 48.6 | 48.8 | 1.50 (0.58–3.88) | 0.40 |
CI, Confidence interval.
a
P values from logistic regression. In all analyses, covariates included age and BMI. In the combined group, race was also taken as a covariate.