Table 5.
Ordinary least squares regression of weekly warfarin dose explained by patient specific variables (n = 130)
| Variable | Coefficient | Standard error |
|---|---|---|
| Demographics | ||
| Age | −0.24 | 0.12* |
| BMI | 0.026 | 0.233 |
| Caucasian | −2.75 | 3.42 |
| Female | −2.55 | 3.08 |
| Medication use | ||
| Amiodarone | −3.35 | 6.60 |
| Aspirin | −1.62 | 2.86 |
| CYP inducer | 17.19 | 5.41** |
| Comorbidities | ||
| CHF | −2.66 | 3.78 |
| Hypothyroidism | −1.99 | 4.22 |
| Prior embolism | −0.36 | 3.01 |
| Other patient characteristics | ||
| Tobacco use | −5.17 | 4.74 |
| Alcohol use | 3.32 | 3.46 |
Notes: R-squared = 0.1676. Adjusted R-squared = 0.0822
*
Statistically significant at the 5% level
**
Statistically significant at the 1% level.