Table 7.

Leading causes of premature death for San Francisco, By sex, 2003–2004

Rank	Underlying cause of death	YLL	YLL %a	Deaths	Average YLLb	ASYRc
Male
1	Violence/assault, all mechanisms	2879.9	3.9	115	25.0	419.8
2	Drug overdose, unintentional	2908.1	3.9	134	21.7	301.8
3	HIV/AIDS	6464.6	8.8	319	20.3	673.1
4	Self-inflicted injuries, all mechanisms	3026.2	4.1	152	19.9	330.2
5	Alcohol use disorders	2228.5	3.0	128	17.4	245.8
6	Cirrhosis of the liver	1586.9	2.2	97	16.4	177.3
7	Liver cancer	2035.6	2.8	154	13.2	248.0
8	Hypertensive heart disease	3379.0	4.6	287	11.8	413.4
9	Diabetes mellitus	1656.5	2.2	147	11.3	198.8
10	Lung, bronchus, and trachea cancers	4134.3	5.6	387	10.7	515.8
11	Colon and rectum cancers	1394.7	1.9	136	10.3	173.5
12	Ischemic heart disease	9853.9	13.4	1103	8.9	1246.1
13	Chronic obstructive pulmonary disease	2241.5	3.0	269	8.3	293.1
14	Cerebrovascular disease	3420.2	4.6	418	8.2	439.3
15	Lower respiratory infections	1801.3	2.4	242	7.4	233.0
Female
1	HIV/AIDS	823.6	1.6	36	22.9	101.7
2	Drug overdose, unintentional	843.8	1.6	37	22.8	96.6
3	Self-inflicted injuries, all mechanisms	992.9	1.9	48	20.7	123.9
4	Breast Cancer	2975.1	5.8	222	13.4	335.8
5	Pancreas cancer	1122.4	2.2	105	10.7	121.4
6	Lung, bronchus, and trachea cancers	3376.2	6.6	326	10.4	361.4
7	Lymphomas and multiple myeloma	852.0	1.7	86	9.9	89.8
8	Colon and rectum cancers	1407.7	2.7	153	9.2	145.3
9	Diabetes mellitus	1207.9	2.4	141	8.6	122.1
10	Hypertensive heart disease	2214.9	4.3	269	8.2	226.1
11	Chronic obstructive pulmonary disease	1651.8	3.2	211	7.8	166.0
12	Cerebrovascular disease	4221.3	8.2	614	6.9	406.6
13	Ischemic heart disease	6721.3	13.1	1017	6.6	646.3
14	Lower respiratory infections	1483.9	2.9	266	5.6	136.4
15	Alzheimer and other dementias	1414.1	2.8	305	4.6	118.3

^a YLL% = YLL ÷ Total YLL from all causes (Step 1: used to select top 15 causes)

^b Average YLL = YLL ÷ Deaths (Step 2: used to subrank top 15 causes)

^c ASYR = Age-standardized YLL rate per 100,000 persons per year