Table 2.
Total number of biochemical conversions and transport processes in the reconstructed metabolic network of A. nidulans and comparison with the metabolic networks of A. niger (316 unique reactions) and S. cerevisiae (843 unique reactions).
| Part of metabolism | Total no. of metabolic reactions network (no. of unique) | No. of unique reactions common to other metabolic networks | |
| A. niger1 | S. cerevisiae | ||
| Biochemical reactions | 1095 (6811) | 191 | 580 |
| C-compound metabolism | 463 (220) | 157 | 160 |
| Energy metabolism | 20 (17) | 11 | 13 |
| Aminoacid metabolism | 238 (171) | 3 | 170 |
| Nucleotide metabolism | 144 (114) | 17 | 114 |
| Lipid metabolism | 175 (122) | 1 | 115 |
| Secondary metabolism | 42 (25) | 1 | 3 |
| Nitrogen and sulphur metabolism | 8 (7) | - | 4 |
| Polymerization, assembly and maintenance | 5 (5) | 1 | 1 |
| Transport processes | 118 (113) | 60 | 59 |
| TOTAL | 1213 (794) | 251 | 639 |
The number of unique reactions in the metabolic network of A. nidulans is shown in parenthesis. The metabolic functions may be or not assigned to ORFs.
1 Note that the metabolic network for A. niger is only detailed for the metabolism of C-compounds (the other parts of the metabolism are represented by lumped reactions) [21], which justifies the relatively low number of reactions in common to both networks in what concerns the other parts of the metabolism.
2 6 non-enzymatic steps are included.