Table 4.
Top 30 reporter metabolites.
| Reporter metabolites | |
| Effect of growth medium | Effect of genotype |
| N-Acetyl-L-glutamate (mitochondrial) | 4-Phospho-L-aspartate |
| Methanol | L-Xylulose |
| Ethanol | D-Sorbitol |
| Ethanol (mitochondrial) | N-Acetyl-D-glucosamine 1-phosphate |
| Acetaldehyde (mitochondrial) | Oxaloglutarate (mitochondrial) |
| Acetaldehyde | Acetate (mitochondrial) |
| Carnitine | Glutathione |
| O-Acetylcarnitine | NH3 (extracellular) |
| N-Acetyl-L-glutamate 5-phosphate (mitochondrial) | 3-(4-Hydroxyphenyl)pyruvate |
| D-Lactate | L-Tyrosine |
| Acetyl-CoA (mitochondrial) | D-Xylulose |
| Formaldehyde | N-(L-Arginino)succinate |
| 3-(4-Hydroxyphenyl)pyruvate | O-Phospho-L-homoserine |
| L-Tyrosine | D-Mannitol |
| L-Xylulose | L-Glutamate |
| D-Sorbitol | N-Acetyl-L-glutamate 5-phosphate (mitochondrial) |
| CoA (mitochondrial) | Acetate |
| N-(L-Arginino)succinate | Starch (extracellular) |
| Acetate (mitochondrial) | Glycogen (extracellular) |
| 2-Hydroxybutane-1,2,4-tricarboxylate (mitochondrial) | N-Acetyl-L-glutamate 5-semialdehyde (mitochondrial) |
| N-Acetyl-L-glutamate 5-semialdehyde (mitochondrial) | Glycerol 3-phosphate |
| Tartrate | NH3 |
| Oxaloglycolate | gamma-Amino-gamma-cyanobutanoate |
| NAD+ (mitochondrial) | Sterigmatocystin |
| NADH (mitochondrial) | Dihydrosterigmatocystin |
| 4-Aminobutyraldehyde (mitochondrial) | Versiconal hemiacetal acetate |
| 4-Aminobutanoate (mitochondrial) | Water (mitochondrial) |
| (S)-Lactaldehyde (mitochondrial) | Xylitol |
| L-Kynurenine | D-Arabitol |
| L-Ornithine (mitochondrial) | N6-(1,2-Dicarboxyethyl)-AMP |
Reporter metabolites identified based on the reconstructed metabolic network and expression data [28]. Two lists are shown, which correspond to highly regulated metabolites (ranked according to p-values) upon a change in the growth medium and in the genotype. Common metabolites to both lists are shown in italic.