Table 4. Relations of selected NOS3 LD regions to bone density/ultrasound indices†.
| Table 4a. Relations of NOS3 LD region 1 haplotypes to BUA in women
| |||||||
|---|---|---|---|---|---|---|---|
| SNP 1 (rs10952296) | SNP 2 (rs1800783) | SNP 3 (rs2070744) | SNP 5 (rs3918169) | Haplotype Frequency | Haplotype p-value* | Global p-value | |
| Haplotype 1A | C | T | T | A | 0.36 | 0.011 (0.33) | 0.094 |
| Haplotype 1B | A | T | T | A | 0.25 | 0.764 | |
| Haplotype 1C | C | A | C | A | 0.23 | 0.112 | |
| Haplotype 1D | C | A | C | G | 0.14 | 0.463 | |
|
Table 4b. Relations of NOS3 LD region 3 haplotypes to Neck BMD in men
| |||||||
| SNP 15 (rs753482) | SNP 16 (rs1065299) | Haplotype Frequency | Haplotype p-value* | Global p-value* | |||
|
| |||||||
| Haplotype 3A | T | G | 0.45 | 0.206 | 0.034 (0.27) | ||
| Haplotype 3B | T | T | 0.32 | 0.317 | |||
| Haplotype 3C | G | G | 0.23 | 0.009 (0.31) | |||
|
| |||||||
†
Bold font where p-values < 0.05.
*
Permuted p-values in parentheses.