Table 2.

Regulation of Bcl2 and Bax By Recombinant IL-1 in IL-1αβ^-/- and IL-1RI^-/- Lines.

Marker	Recombinant IL-1	Ratio Marker/Actin*
		wt2	IL-1α-/-3	IL-1β-/-3	IL-1αβ-/-11	IL-1RI-/-1
Bcl2	None	0.25	0.25	0.10	1.00	0.50
	IL-1α	0.35	0.35	0.15	0.75	0.60
	IL-1β	0.25	0.35	0.10	0.50	0.60
IL-1α + IL-1β	0.30	0.35	0.10	0.45	1.2
Bax	None	0.40	0.35	0.35	0.75	1.00
	IL-1α	0.55	0.30	0.40	0.80	1.00
	IL-1β	0.45	0.30	0.35	0.60	1.10
	IL-1α + IL-1β	0.40	0.30	0.30	0.50	1.15

Cells were cultured for 24 hours in the presence of 10 ng/ml recombinant IL-1.

^*Strong differences in the marker/actin ratio are indicated in bold.