Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2008 May 28;3(5):e2303. doi: 10.1371/journal.pone.0002303

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Lange et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

Ovarian cancer cells (SKOV-3) were treated with 0, 0.4, 0.8 and 1.6 µM Fe-SP or SP (Ctr.) for 24 or 48 h. Cell cycle analysis by FACS based on propidium-iodide intercalation into the cellular chromatin was carried out as described (Materials and Methods). Data are presented as (A) relative fluorescence intensity in a 2-dimensional FACS profile (ModFit LT software; black lines = data line and model fit line of entire population; shaded areas = model components/subpopulations of G0/G1, S, G2/M, apoptotic cells), example shown for 48 h treatment with 0.8 µM compound, or as (B) comprehensive bar diagram of all data. Standardized gating was used for all samples. Ten thousand events were analyzed for each sample.