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. 2008 May 14;336(7653):1121–1123. doi: 10.1136/bmj.39548.738368.BE

Table 1 .

Mean baseline characteristics and differences in blood pressure at follow-up between randomised groups in subgroups of younger and older adults

Treatment comparison Age <65 (n=96 466) Age ≥65 (n=94 140)
Total No Age (years) Baseline SBP/DBP (mm Hg) Difference in SBP/DBP (mm Hg) % Men Total No Age (years) Baseline SBP/DBP (mm Hg) Difference in SBP/DBP (mm Hg) % Men
ACE-I v placebo 19 154 57 137/82 −4.6/−2.1 79 15 923 70 143/80 −4.2/−2.0 72
CA v placebo 2 597 58 149/83 −7.2/−2.9 60 4354 72 168/84 −9.3/−3.8 37
More v less* 15 335 57 165/104 −4.3/−3.5 57 6647 70 173/104 −3.5/−3.4 47
ARB v other 1464 56 151/85 −1.7/−0.3 64 6338 75 163/89 −2.0/−1.2 39
ACE-I v D/BB 22 088 55 153/93 1.3/0.2 54 25 342 73 161/88 2.0/0.5 49
CA v D/BB 43 594 58 154/93 1.1/−0.2 50 46 185 72 157/87 0.5/−0.4 46
ACE-I v CA 10 049 59 145/87 0.9/0.6 55 16 310 73 160/87 1.0/1.0 49

SBP/DBP=systolic/diastolic blood pressure; ACE-I=angiotensin converting enzyme inhibitor; CA=calcium antagonist; ARB=angiotensin receptor blocker; D/BB=diuretic or β blocker.

*More v less intensive blood pressure lowering regimen.