Table 2.
A subset of genes mediating the VPC cell-fate decision were also required for normal VPC quiescence
| genotype1 | no. extra VPCs2 | n3 |
|---|---|---|
| N2 | 0 | many |
| lin-12(n950) | 0 | 71 |
| lip-1(RNAi) | 0 | 25 |
| sli-1(RNAi) | 0 | 26 |
| let-60(n2022) | 0 | 19 |
| let-60(n1046gf) | 0 | 20 |
| let-60(ga89), 15°C | 0 | 23 |
| let-60(ga89), 25°C | 0 | 25 |
| gap-2(tm748) | 0 | 38 |
| sos-1(cs41), 15°C | 0 | 24 |
| sos-1(cs41), 25°C | 0 | 30 |
| mpk-1(ga117) | 0 | 34 |
| lin-1(he117) | 0.03 ± 0.2 | 35 |
| lin-1(he119) | 0.08 ± 0.3 | 59 |
| lin-1(e1777) | 0.06 ± 0.3 | 31 |
| lin-1(n304) | 0.03 ± 0.2 | 63 |
| lin-31(he136) | 0.4 ± 0.9 | 64 |
| lin-31(n301) | 0.3 ± 0.5 | 49 |
| lin-31(n1053) | 0.3 ± 0.6 | 64 |
| lin-31(n301); lin-1(he119) | 0.8 ± 1.2 | 25 |
| lin-31(n301); lin-1(he117) | 0.8 ± 0.9 | 89 |
| lin-31(he136); lin-35(RNAi) | 1.4 ± 1.0 | 14 |
| lin-1(he119); lin-35(RNAi) | 0 | 35 |
| lin-35(RNAi) | 0 | 30 |
| lin-25(e1446) | 0.8 ± 0.6 | 44 |
| mdt-23/sur-2(ku9) | 0.6 ± 0.3 | 35 |
| sur-5(RNAi) | 0 | 25 |
| lin-8(n2403); lin-36(n766) | 0 | 19 |
| lin-15(n765) | 0 | 27 |
1
all strains were grown at 20° C, unless indicated.
2
presented as average number of VPCs displaying extra divisions/animal examined ± SD.
3
number of L2 animals examined.