Table 3.
Characteristics of children who underwent serum testing
| Female
|
Male
|
|||||
|---|---|---|---|---|---|---|
| PCOS (n = 7) | Control (n = 11) | P value | PCOS (n = 10) | Control (n = 6) | P value | |
| Biometrical | ||||||
| Age (yr) | 11.6 (3.0) | 11.1 (2.5) | 0.73 | 11.1 (2.1) | 12.0 (1.3) | 0.31 |
| BMI (kg/m2) | 23.3 (6.3) | 20.5 (3.3) | 0.31 | 21.9 (4.9) | 19.9 (3.0) | 0.33 |
| Waist circumference (cm) | 72.1 (14.4) | 70.9 (7.5) | 0.84 | 80.0 (19.8) | 74.3 (3.8) | 0.39 |
| Waist to hip ratio | 0.8 (0.1) | 0.8 (0.1) | 0.64 | 0.9 (0.1) | 0.8 (0.0) | 0.28 |
| Systolic blood pressure (mm Hg) | 113.4 (14.8) | 112.0 (11.2) | 0.83 | 114.1 (20.9) | 104.8 (9.5) | 0.25 |
| Diastolic blood pressure (mm Hg) | 68.7 (10.8) | 64.7 (5.1) | 0.39 | 67.4 (10.1) | 64.0 (6.2) | 0.42 |
| Reproductive (serum) | ||||||
| LH (mIU/h) | 7.3 (12.7) | 11.9 (20.7) | 0.61 | 2.5 (1.0) | 2.0 (0.0) | 0.34 |
| FSH (mIU/h) | 5.1 (2.4) | 6.2 (2.9) | 0.43 | 3.6 (2.1) | 5.3 (3.9) | 0.47 |
| Testosterone (ng/dl) | 24.1 (10.7) | 22.6 (18.2) | 0.83 | 173.2 (229.5) | 226.2 (256.5) | 0.69 |
| DHEAS (ng/ml) | 1061.3 (425.4) | 847.0 (409.5) | 0.31 | 1138.6 (785.9) | 635.2 (327.1) | 0.10 |
| Metabolic | ||||||
| Fasting insulin (μU/ml) | 18.1 (2.3) | 15.5 (4.3) | 0.11 | 22.3 (16.9) | 15.0 (7.7) | 0.26 |
| Insulin at 120 min (μU/ml) | 61.6 (31.0) | 44.1 (20.3) | 0.22 | 55.4 (39.7) | 55.8 (25.8) | 0.98 |
| Fasting glucose (mg/dl) | 73.9 (9.7) | 79.7 (7.1) | 0.20 | 79.6 (6.4) | 77.3 (9.3) | 0.61 |
| Glucose at 120 min (mg/dl) | 77.3 (16.0) | 82.6 (9.3) | 0.46 | 90.3 (10.1) | 86.8 (14.7) | 0.63 |
| HOMA IR | 3.3 (0.6) | 3.0 (1.0) | 0.54 | 4.3 (3.0) | 2.9 (1.9) | 0.29 |
| ISI (from OGTT) | 97.2 (21.7) | 95.4 (10.3) | 0.85 | 90.3 (17.6) | 93.9 (24.1) | 0.76 |
| Total cholesterol (mg/dl) | 153.0 (15.7) | 145.3 (9.9) | 0.33 | 150.8 (27.0) | 144.4 (16.1) | 0.59 |
| HDL-C (mg/dl) | 48.8 (14.7) | 49.0 (17.1) | 0.99 | 44.3 (8.0) | 32.8 (14.6) | 0.16 |
| LDL-C (mg/dl) | 86.7 (11.7) | 83.6 (22.9) | 0.76 | 90.6 (21.0) | 90.0 (21.1) | 0.96 |
| Triglycerides (mg/dl) | 87.3 (34.7) | 63.6 (14.2) | 0.17 | 78.6 (23.6) | 108.6 (26.7) | 0.07 |
Values are expressed as mean (sd). Conversion factors to International System of Units: testostorone × 3.467 (nmol/liter), DHEAS × 0.002714 (μmol/liter), glucose × 0.0551 (mmol/liter), insulin × 7.175 (pmol/liter), cholesterol × 0.0259 9 mmol/liter, and triglycerides × 0.0113 (mmol/liter). ISI, International sensitivity index; LDL-C, low-density lipoprotein cholesterol.