Table 2.
Summary statistics and P values for health status and mood measures during the two treatment arms
| Measure | Baseline (mean ± sem) | Euthyroid (mean ± sem) | Thyrotoxic (mean ± sem) | P value (paired t test) | Adjusted P values |
|---|---|---|---|---|---|
| SF-36 | |||||
| MCS | 51.72 ± 1.02 | 50.69 ± 1.46 | 52.71 ± 1.16 | 0.15 | Treatment: 0.15 |
| PCS | 51.91 ± 1.33 | 56.59 ± 0.61 | 54.75 ± 0.83 | 0.01 | Treatment: 0.01 |
| Treatment test: 0.008 | |||||
| BP | 76.00 ± 4.09 | 84.43 ± 3.01 | 81.87 ± 3.14 | 0.18 | 0.22 |
| GH | 80.84 ± 2.65 | 85.03 ± 2.23 | 81.55 ± 2.28 | 0.06 | 0.06 |
| MH | 80.38 ± 1.60 | 78.40 ± 2.28 | 84.13 ± 1.55 | 0.02 | 0.01 |
| VT | 59.84 ± 2.83 | 66.83 ± 2.57 | 69.03 ± 1.96 | 0.45 | 0.42 |
| PFa | 91.72 ± 2.82 | 96.33 ± 1.10 | 94.52 ± 1.56 | 0.50 | |
| RPa | 76.56 ± 6.54 | 93.33 ± 3.16 | 93.33 ± 3.38 | >0.99 | |
| SFa | 86.33 ± 3.86 | 93.33 ± 2.05 | 89.58 ± 3.55 | >0.99 | |
| REa | 91.67 ± 2.99 | 86.67 ± 4.40 | 88.89 ± 4.33 | 0.73 | |
| POMS | |||||
| A | 42.13 ± 0.89 | 44.50 ± 1.11 | 43.16 ± 1.21 | 0.34 | Treatment: 0.002 |
| C | 41.78 ± 1.07 | 42.44 ± 1.54 | 40.00 ± 1.03 | 0.04 | |
| D | 41.16 ± 0.73 | 42.66 ± 1.06 | 40.44 ± 0.65 | 0.06 | |
| F | 44.72 ± 1.37 | 43.38 ± 1.16 | 42.59 ± 1.03 | 0.51 | |
| T | 41.66 ± 1.06 | 42.53 ± 1.17 | 39.16 ± 1.64 | 0.05 | |
| V | 51.84 ± 1.10 | 53.16 ± 1.39 | 55.75 ± 1.28 | 0.11 | 0.11 |
P values for unadjusted paired t tests comparing the two arms of the study are shown in the fifth column. Adjusted P values in the repeated measures analysis are shown in the sixth column. These P values were adjusted for age, years of education, WAIS-R, and baseline measure for that particular variable. Significant results are highlighted in bold. For the adjusted analyses, treatment test P values were examined initially. If the treatment test P value was more than 0.1, indicating no treatment-test interaction, it is not shown in the table, and only the overall treatment effect is shown. If the treatment test P value was 0.1 or less, indicating a possible treatment-test interaction, this value is listed in the table, and subsequent analyses were done for individual measures. A, Anxiety; BP, bodily pain; C, confusion; D, depression; F, fatigue; PF, physical functioning; RE, role emotional; RP, role physical; SF, social functioning; T, tension; V, vigor; VT, vitality.
Raw scores compared using an exact McNemar’s test because many values were at ceiling.