Table 3.
Cox proportional hazard: Crude and adjusted risks for mortality for each covariate, including mean serum albumin <3.5/3.2 versus ≥3.5/3.2 and <4.0/3/7 versus ≥4.0/3.7 g/dl, n = 675a
| Covariates | HR, Crude (95% CI) | HR, Adjusted (95% CI) |
|---|---|---|
| Serum albumin ≥3.5/3.2 and < 4.0/3/7 versus <3.5/3.2 g/dl | 0.66 (0.33 to 1.33) | 0.74 (0.35 to 1.60) |
| Serum albumin ≥4.0/3.7 versus <3.5/3.2 g/dl | 0.42 (0.20 to 0.89)b | 0.43 (0.19 to 0.96)b |
| Age (yr) | 1.11 (0.91 to 1.34) | 1.16 (0.94 to 1.43) |
| White race | 1.21 (0.70 to 2.11) | 1.30 (0.69 to 2.45) |
| Male gender | 1.00 (0.58 to 1.71) | 1.03 (0.57 to 1.87) |
| Hispanic ethnicity | 1.06 (0.55 to 2.03) | 1.29 (0.60 to 2.74) |
| Nephrotic syndrome/FSGS | 0.57 (0.25 to 1.34) | 0.56 (0.22 to 1.41) |
| HD access type: catheter | 1.23 (0.77 to 1.98) | 1.23 (0.73 to 2.07) |
| Mean hemoglobin ≥11 versus < 11 g/dl | 0.40 (0.22 to 0.71)b | 0.40 (0.20 to 0.78)b |
| Mean serum ferritin (ng/ml) | ||
| 100 to 500 | Reference | Reference |
| <100 | 0.89 (0.43 to 1.84) | 0.86 (0.38 to 1.96) |
| >500 | 1.49 (0.76 to 2.92) | 1.37 (0.70 to 2.69) |
| Mean BMI-for-age percentile | ||
| 5th through 85th | Reference | Reference |
| <5th | 1.90 (0.92 to 3.92) | 2.05 (0.98 to 4.31) |
| ≥85th through 95th | 0.59 (0.18 to 1.95) | 0.55 (0.15 to 2.01) |
| ≥95th | 1.50 (0.70 to 3.25) | 1.54 (0.67 to 3.51) |
| Mean spKt/V ≥1.2 versus <1.2 | 1.08 (0.60 to 1.98) | 0.97 (0.50 to 1.86) |
| Mean dialysis vintage ≥180 versus <180 d | 1.29 (0.71 to 2.36) | 2.26 (1.11 to 4.59)b |
| Mean ESRD duration (yr) | ||
| <2 | Reference | Reference |
| 2 to 5 | 0.86 (0.44 to 1.69) | 0.81 (0.42 to 1.57) |
| ≥5 | 0.70 (0.34 to 1.43) | 0.60 (0.28 to 1.27) |
| PD exposure | 0.96 (0.34 to 2.72) | 1.12 (0.38 to 3.35) |
a
CI, confidence interval; HR, hazard ratio; PD, peritoneal dialysis.
b
P < 0.05