Table 3.

Urine NGAL measurements in ng/ml at various time points after cardiopulmonary bypass

Time After CPB (h)	No AKI (n = 97): NGAL, ng/ml (mean ± SEM)	AKI (n = 99): NGAL, ng/ml (mean ± SEM)	No AKI (n = 97): NGAL, ng/ml [median (range)]	AKI (n = 99): NGAL, ng/ml [median (range)]	P	AUC
0	14.8 ± 2.7	43.6 ± 14.2	5.7 (0.1–138)	9.3 (0.6–976)	0.09	0.59
2	53.0 ± 20.7	646.3 ± 69.8	4.0 (0.2–1557)	457 (3.6–2778)	<0.0001	0.93
4	50.6 ± 14.4	1098.8 ± 87.1	8.2 (0.9–814)	1080 (3.4–2580)	<0.0001	0.96
6	28.3 ± 6.9	1113.4 ± 88.8	8.4 (1.5–422)	948 (20–2841)	<0.0001	0.98
8	30.5 ± 8.9	638.7 ± 69.8	7.6 (0.9–652)	444 (3.3–2571)	<0.0001	0.94
12	26.9 ± 5.3	300.2 ± 42.7	9.5 (0.6–322)	170 (2.8–2346)	<0.0001	0.88
24	20.8 ± 4.7	116.0 ± 28.0	7.6 (0.3–353)	25 (2.8–1900)	0.0005	0.76
36	11.2 ± 1.8	92.8 ± 39.8	9.1 (1.0–58)	16 (0.5–2581)	0.001	0.69
48	16.3 ± 2.9	176.6 ± 54.9	7.8 (0.5–128)	22 (1.0–2809)	0.005	0.72
72	30.9 ± 13.7	53.2 ± 23.3	7.7 (1.8–220)	7.9 (0.6–558)	0.5	0.51

At each time point, the calculated area under the curve (AUC) for prediction of AKI is also shown.