Table 6.

Correlation of NGAL urine measurements (ng/ml) at 2, 4, and 6 h after CPB surgery with independent clinical factors

Comparison parameter	Hour	Correlation Type	R	P	AUC
NGAL versus Δ creatinine (%)	2	Nonparametric	0.66	<0.0001	—
NGAL versus LOS (days)	2	Nonparametric	0.42	<0.0001	—
NGAL versus days in AKI	2	Nonparametric	0.73	<0.0001	—
NGAL versus dialysis	2	Logistic	0.38	0.01	0.86
NGAL versus death	2	Logistic	0.53	0.01	0.91
NGAL versus Δ creatinine (%)	4	Nonparametric	0.68	<0.0001	—
NGAL versus LOS (days)	4	Nonparametric	0.44	<0.0001	—
NGAL versus days in AKI	4	Nonparametric	0.77	<0.0001	—
NGAL versus dialysis	4	Logistic	0.30	0.1 (NS)	0.80
NGAL versus death	4	Logistic	0.33	0.1 (NS)	0.81
NGAL versus Δ creatinine (%)	6	Nonparametric	0.72	<0.0001	—
NGAL versus LOS (days)	6	Nonparametric	0.49	<0.0001	—
NGAL versus days in AKI	6	Nonparametric	0.80	<0.0001	—
NGAL versus dialysis	6	Logistic	0.45	0.06 (NS)	0.90
NGAL versus death	6	Logistic	0.15	0.48 (NS)	0.67

LOS, length of hospital stay (days); Δ creatinine, percent change in serum creatinine from baseline; AUC, area under the curve values from a typical ROC plot (for predicting dialysis, n = 4; and death, n = 3); —, not applicable; NS, not significant. The predictive modeling for death and dialysis events were limited due to the size of the study.