Table 2.
Metabolic characteristics of recipients with NGM or a GMA
| Characteristic | NGM(n = 252) | GMA(n = 119) | P |
|---|---|---|---|
| BMI (kg/m2; mean ± SD) | 26.5 ± 4.5 | 28.0 ± 4.3 | 0.010 |
| BMI increase after transplantation (median [range]) | 1.65 (0.45 to 3.48) | 2.91 (1.19 to 4.40) | 0.003 |
| Weight gain after transplantation (kg; median [range]) | 4.5 (1.3 to 9.8) | 7.7 (3.0 to 12.0) | 0.006 |
| Total cholesterol (mg/dl; mean ± SD) | 189 ± 33 | 190 ± 32 | NS |
| LDL cholesterol (mg/dl; mean ± SD) | 103 ± 28 | 99 ± 28 | NS |
| HDL cholesterol (mg/dl; median [range]) | 56 (47 to 69) | 53 (43 to 65) | NS |
| Tg (mg/dl; median [range]) | 117 (84 to 150) | 147 (105 to 183) | <0.001 |
| Tg/HDL cholesterol (median [range]) | 2.05 (1.30 to 2.90) | 2.80 (1.70 to 3.70) | <0.001 |
| OGTT glucose 0 (mg/dl; median [range]) | 87 (81 to 94) | 99 (91 to 104) | <0.001 |
| OGTT glucose 120 (mg/dl; median [range]) | 101 (85 to 117) | 160 (140 to 193) | <0.001 |
| Glycated hemoglobin (%; median [range]) | 5.2 (4.8 to 5.6) | 5.5 (5.0 to 5.9) | <0.001 |
| First posttransplantation year profile | |||
| 3-mo glucose (mg/dl; median [range]) | 90 (81 to 100) | 96 (86 to 106) | <0.001 |
| 3-mo IFG (%) | 24 | 40 | 0.005 |
| 6-mo glucose (mg/dl; median [range]) | 88 (81 to 95) | 94 (86 to 104) | <0.001 |
| 6-mo IFG (%) | 16 | 31 | 0.002 |
| 12-mo glucose (mg/dl; median [range]) | 86 (81 to 93) | 94 (87 to 103) | <0.001 |
| 12-mo IFG (%) | 10 | 37 | <0.001 |
| transient NODAT (first year; %) | 5.9 | 3.4 | NS |
| 3-mo Tg (mg/dl; median [range]) | 128 (91 to 171) | 147 (106 to 183) | 0.050 |
| 6-mo Tg (mg/dl; median [range]) | 119 (89 to 172) | 135 (105 to 173) | 0.050 |
| 12-mo Tg (mg/dl; median [range]) | 112 (88 to 157) | 149 (115 to 186) | <0.001 |
| 12-mo Tg/HDL cholesterol (median [range]) | 2.1 (1.3 to 3.1) | 2.6 (1.8 to 3.6) | 0.005 |
| 12-mo Total cholesterol (mg/dl; mean ± SD) | 198 ± 35 | 199 ± 30 | NS |
| 12-mo HDL cholesterol (mg/dl; median [range]) | 55 (45 to 68) | 56 (46 to 68) | NS |
| 12-mo LDL cholesterol (mg/dl; mean ± SD) | 114 ± 38 | 111 ± 29 | NS |
aGMA include IFG, IGT, and provisional diagnosis of diabetes. BMI, body mass index. OGTT, oral glucose tolerance test; NODAT, new-onset diabetes after transplantation; Tg, triglycerides.