Figure 2.

Neutrophil infiltration in cisplatin nephrotoxicity requires the presence of TLR4. Sections of kidney harvested from C57BL/6 (A) or Tlr4(−/−) (B) mice 72 h after cisplatin injection were stained for neutrophils as described in “Concise Methods.” (C) Thirty ×40 fields of kidney cortex were examined from each animal. The total number of neutrophils in those 30 fields is presented. ⁺P < 0.01 versus all others; n = 3 to 7.