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Effects of cisplatin on urine cytokine excretion. Urine samples were obtained from C57BL/6 or Tlr4(−/−) mice 72 h after saline or cisplatin. Cytokine levels were normalized to the creatinine concentration in the urine. *P < 0.05 C57BL/6 versus Tlr4(−/−); n = 3 to 5. UD, undetectable.