Table 1.
Characteristics of patients with IgAN, their relatives, and controls
| Familial IgAN Patients | Relatives of Familial IgAN Patients | Sporadic IgAN Patients | Relatives of Sporadic IgAN Patients | Controls | |
|---|---|---|---|---|---|
| N | 5 | 64 | 84 | 202 | 141 |
| Age, yr | 44 ± 5 | 42 ± 18 | 39 ± 13 | 43 ± 16 | 37 ± 13 |
| Ethnicity, white/black | 5/0 | 63/0 | 81/3 | 192/10 | 141/0 |
| Gender, male/female | 5/0 | 28/35 | 48/37 | 67/125 | 73/68 |
| BMI, kg/m2 | 32 ± 11 | 27.5 ± 6 | 31.5 ± 8 | 29.5 ± 7 | 26.5 ± 5 |
| GFR, ml/min/1.73 m2 | 43 ± 15 | 76 ± 17 | 61.5 ± 37 | 83 ± 21 | 88 ± 17 |
| GFR <30, N | 1 | 0 | 19 | 0 | 0 |
| Systolic BP, mm Hg | 125 ± 5 | 129 ± 16 | 131 ± 20 | 130 ± 20 | 123 ± 13 |
| Diastolic BP, mm Hg | 82 ± 9 | 77 ± 9 | 77 ± 10 | 75 ± 10 | 73 ± 7 |
| Hypertension, N | 5 | 17 | 56 | 67 | 21 |
| Urine P/C | 0.3 ± 0.1 | 0.1 ± 0.1 | 1.0 ± 1.4 | 0.2 ± 1.3 | — |
| Urine P/C > 3, N | 0 | 0 | 5 | 1 | — |
| Hematuria, N (%) | 5 (100) | 6 (9) | 33 (40) | 7 (3.5) | 0 |
Values are mean ± SD. BMI, body mass index; GFR, glomerular filtration rate; BP, blood pressure; P/C, protein to creatinine ratio; —, not applicable.