Table 3.

Specific activity of sEH in different brain regions compared with the liver

Human tissues	t-DPPO activity (nmol.min−1.mg protein−1) ± SEM
Liver	16.2 ± 3.6
Frontal lobe	1.7 ± 0.4*
Occipital lobe	1.7 ± 0.3*
Parietal lobe	2.1 ± 0.2*
Temporal lobe	1.8 ± 0.1*
Thalamus	1.8 ± 0.1*

^*Significant statistical difference from liver (p≤0.05).

Results are normalized to total protein concentration. sEH, soluble epoxide hydrolase; t-DPPO, trans-[2-³H] 1, 3-diphenylpropene oxide.