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. 2008 Apr 22;8:45. doi: 10.1186/1471-2229-8-45

Table 3.

Aromatic/arginine filter of PpMIPs and MIPs of the XIP subfamily

NPA motifs Ar/R selectivity filtera


MIP protein(s)b Loop B Loop E H2 H5 LE1 LE2 Alt. H5c
PpPIPs NPA NPA F H T R
PpTIPs NPA NPG H I A R
PpNIP3.1 NPA NPV A I A R
PpNIP5s NPA NPA F A A R
PpNIP6.1 NPA NPM G V A R
PpSIPs NPT NPA V V P N
PpGIP1.1 NPA NPA F V P R
PpHIP1.1 NPA NPA H H A R
PpXIP1.1 NPC NPA Q A A R A
PpXIP1.2 NPS NPA Q I A R Q
DN837617 NPI NPA L Q A R S
DY275505 NPL NPA V V A R T
AM455454.1 NPV NPA V V A R T
557139 NPI NPA V V A R T
829126 NPI NPA V V A R T
759781 NPI NPA V V A R T
EG666650 SPT NPA V V V R T
DR936893 DT742029 NPT NPS V V V R S
CK746370 D T60037 NPI NPA V I V R G
767334 NPL NPA A V A R T
CK295158 NPV NPA I V A R T
BT014197 NPV NPA I V A R T
AM455454.2 NPI NPA I V A R T
821124 NPA NPA I V V R T
EG656577 NPV NPA I V V R T
CO092422 NPV NPA I V V R T
XM_639170 NPS NPA H S F R I

a The ar/R filter is defined by four amino acid residues: one in helix 2, one in helix 5 and two in loop E b The PpMIPs are identified with their proposed names and the other MIPs are identified by their GenBank accession numbers c Alternative residue at H5 position due to alignment of conserved glycines in helix 5, however this also introduces two extra amino acids between helix 5 and the second NPA box