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. Author manuscript; available in PMC: 2008 May 17.
Published in final edited form as: Circ Res. 2007 Mar 15;100(7):1089–1098. doi: 10.1161/01.RES.0000264081.78659.45

Figure 3.

Figure 3

Histological staining demonstrating that iNOS deletion attenuated TAC-induced myocardial fibrosis (A, B), cardiac myocyte hypertrophy (C, D), and the increase of myocardial MMP2 activity (E,F). MTS: Masson's trichrome staining, blue staining indicates fibrosis; WGA: Staining for wheat germ agglutinin with FITC-conjugated Flur-488 (Invitrogen), bright green staining indicates the area of the matrix and cell membrane. Summarized average data are from 4 representative mice per group. *p<0.05 compared to the corresponding control; #p<0.05 as compared to Wt-TAC.