TABLE 4.
Shared genetic effects between basal and HCHF diets and evidence for genotype-by-diet interaction affecting Lp-PLA2 activity and LDL-C concentration in pedigreed baboons
Lp-PLA2 | LDL-C | |
---|---|---|
ρG (between basal and HCHF diets) | 0.94 (0.03) | 0.86 (0.05) |
ρG2 (between basal and HCHF diets) | 0.89 | 0.73 |
P[ρG = 1] | 0.0017 | 0.00001 |
P[ρG = 0] | 2.31 × 10−25 | 4.42 × 10−19 |
P[σG(BASAL)2 = σG(HCHF)2 | NS | NS |
Maximum likelihood parameter estimates. Parentheses enclose SEM.