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. Author manuscript; available in PMC: 2008 Jul 1.
Published in final edited form as: Drug Metab Dispos. 2007 Apr 19;35(7):1174–1181. doi: 10.1124/dmd.107.014910

Fig. 5.

Fig. 5

Binding of CPR and cyt b5 to CYP2C9 (200 nM) as measured by the difference between the peak heights of the high spin (HS) and low spin (LS) heme iron components in P450 absolute spectra. (A) CPR binding (●), cyt b5 binding (○), and CPR binding with equimolar CYP2C9/cyt b5 (▼). (B) cyt b5 binding with equimolar CYP2C9/CPR (low cyt b5 concentrations shown in inset for clarity).