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. Author manuscript; available in PMC: 2008 May 19.
Published in final edited form as: FASEB J. 2007 Dec 27;22(5):1491–1501. doi: 10.1096/fj.07-9411com

Figure 7.

Figure 7

Effects of COX-1 deficiency on LPS-induced oxidative stress. COX-1+/+ and COX-1−/− mice received icv injection of LPS or vehicle 24 h before sacrifice. (A) Representative immunoblot of protein carbonyls. (B) Quantification of protein carbonyls. Data are mean ± SEM (n = 4). **P < 0.01 vs. corresponding vehicle-injected COX-1+/+ mice; #P < 0.05, ##P < 0.01 vs. corresponding LPS-injected COX-1+/+ mice. (C-F) Representative photomicrographs of nitrotyrosine immunohistochemistry in the hippocampus. Scale bar, 100 μm.