Table 1.
Morphometric and Physiological Analyses of Wt and NRG1 type III+/− Nerves
+/+ | +/− | ||
---|---|---|---|
% myelinated | 40.5% | 27.8% | |
% unmyelinated | 59.5% | 72.2% | p < 0.0001 |
g ratios | 0.68 ± 0.004 | 0.73 ± 0.004 | p < 0.0001 |
Unsegregated axons/Remak bundle | 5% | 25% | p < 0.0001 |
# axons/Remak bundle | 8.7 | 13.1 | p < 0.0001 |
NCV Myelinated (37°C) | 39.89 ± 3.75 | 31.93 ± 2.29 | p = 0.01 |
NCV C fibers (37°C) | 0.61 ± 0.04 | 0.46 ± 0.02 | p = 0.006 |
Summary of the morphometric analyses performed in adult wt and NRG1 type III+/− mice showing the g ratio values for sciatic nerve, the percentage of unmyelinated and myelinated fibers in sciatic nerves, and the percentage of unsegregated axons in Remak bundles. Morphologic analyses were performed using NIH Image J and Prism software. G ratios were calculated from the data set in Figure S4.