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. Author manuscript; available in PMC: 2008 May 19.
Published in final edited form as: Bioinformatics. 2007 Jan 19;23(6):673–679. doi: 10.1093/bioinformatics/btm009

Table 2.

Glimmer3 prediction accuracy when trained on confirmed genes

Genome
Glimmer3 Predictions
versus Glimmer2.13
Organism GC% # Genes 3′ Matches 5′ & 3′ Matches Extra 3′ Match 5′ & 3′ Extra
A.fulgidus 49 1165 1162 99.7% 841 72.2% 1308 −2 −67 −59
B.anthracis 35 3132 3119 99.6% 2717 86.7% 2345 +6 +726 −77
B.subtilis 44 1576 1559 98.9% 1379 87.5% 2886 +11 +413 −539
C.tepidum 57 1292 1284 99.4% 867 67.1% 778 +2 −33 −190
C.perfringens 29 1504 1501 99.8% 1360 90.4% 1177 −1 +244 −28
E.coli 51 3603 3525 97.8% 3014 83.7% 942 +16 +693 −632
G.sulfurreducens 61 2351 2320 98.7% 1883 80.1% 1107 +15 +541 −380
H.pylori 39 915 908 99.2% 785 85.8% 774 +1 +46 −94
P.fluorescens 63 4535 4484 98.9% 3412 75.2% 1896 +14 +731 −704
R.solanacearum 67 2512 2468 98.2% 1922 76.5% 1091 +72 +646 −326
S.epidermidis 32 1650 1646 99.8% 1496 90.7% 767 +3 +338 −66
T.pallidum 53 575 569 99.0% 397 69.0% 568 +3 +55 −296
U.parvum 26 327 325 99.4% 292 89.3% 297 0 +19 −17
Averages: 99.1% 81.1% +11 +335 −262

For each genome, ‘#Genes’ counts genes in the NCBI annotation that are at least 90bp long, do not have frame shifts or internal stop codons, and whose function description does not contain the string ‘hypothetical’. Both Glimmer3 and Glimmer2 were run with the same options and training/test sets in an 8-way cross-validation experiment on this set of genes. A prediction is a 3′ match iff it has the same reading frame and stop codon as a gene. 5′ & 3′ matches are predictions with the same start and stop codon as the annotation. Extra predictions are those that are not matches. The ‘versus Glimmer2’ column is the Glimmer3 value minus the corresponding Glimmer2 value.