Table 2.

Loss of Isc1 sensitizes Cn to the Pma1 inhibitor ebselen^a

Strain	pH 7 (μM)	pH 4 (μM)
WT	3.12	2.48
Δisc1	3.12	0.78*
Δisc1REC	3.12	3.12
GAL7:IPC1-glucose	3.12	0.39*

^*P<0.05 (pH 4 versus 7).

^aEbselen is fungicidal to WT, Δisc1, Δisc1^REC, and GAL7:IPC1 strains at an MFC of 3.12 μM at a neutral pH. The Δisc1 mutant and GAL7:IPC1 strain grown on glucose (Ipc1 downregulated) showed MFCs of 0.78 and 0.39 μM, respectively. Results are the means of three separate experiments.