Table 3.
Proportion of patients with SCLC treated with topotecan who had symptom improvement
| Symptom | Patients showing improvement, n (%) N = 260a |
|---|---|
| Insomnia | 51 (19.6) |
| Cough | 46 (17.7) |
| Anorexia | 45 (17.3) |
| Dyspnea | 41 (15.8) |
| Chest pain | 31 (11.9) |
| Hoarseness | 30 (11.5) |
| Hemoptysis | 9 (3.5) |
| Interference with daily activitiesb | 26 (16.1) |
| Fatigueb | 22 (13.7) |
a
Note: Symptom palliation was evaluated in only 3 of the 5 trials in this retrospective study
b
Evaluated in only 2 of the 3 trials (N = 161)
Data from Treat et al (2004).