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Treatment schedule
| Group no. | Group code | Time of 1.0 mg/kg rhu MAb HER-2 administration, days | Time of 5.0 mg/kg doxorubicin administration, days |
|---|---|---|---|
| 1 | C | — | — |
| 2 | H0 | 0 | — |
| 3 | H1 | 1 | — |
| 4 | H4 | 4 | — |
| 5 | D0 | — | 0 |
| 6 | D1 | — | 1 |
| 7 | D4 | — | 4 |
| 8 | H0D0 | 0 | 0 |
| 9 | H0D1 | 0 | 1 |
| 10 | H0D4 | 0 | 4 |
| 11 | H1D0 | 1 | 0 |
| 12 | H4D0 | 4 | 0 |
Day 0 is 14 days after xenograft implantation. There were seven mice per group.
